KMID : 0613820060160060932
|
|
Journal of Life Science 2006 Volume.16 No. 6 p.932 ~ p.937
|
|
Effects of Cheonggukjang on Lipid Metabolism in Female Rats Fed Cholesterol Diet
|
|
Lee Choong-Un
Koh Jin-Bog
|
|
Abstract
|
|
|
The effects of cheonggukjang (CK) on the weight gains, serum and hepatic lipids levels were investigated in adult female rats fed the cholesterol diets. Sprague-Dawley strain rats were given four different types of diet for 4 weeks, respectively: a normal diet, a control diet (10% fat + 0.5% cholesterol), a 5% or 10% CK diets (control diet + 5% or 10% CK powder). The body weights, food intake and food efficiency ratios, and the uterine fat pad weights of 5% CK and 10% CK groups were more significantly decreased than those of the control group. The liver cholesterol and triglyceride levels were significantly lower of the 10% CK group than those of the control group. The concentrations of serum triglyceride, total cholesterol, LDL+VLDL-cholesterol, and atherogenic index ratios were significantly decreased in the 10% CK group compared with those in the control group. The HDL-cholesterol/total-cholesterol ratios was significantly increased in the 10% CK group compared with those in the control group. The fecal total lipid excretion of the 5% and 10% CK groups were more increased than those in the control group. These results showed that the 10% cheonggukjang feeding decreased the triglyceride, total cholesterol, LDL+VLDL-cholesterol and atherogenic index ratios in serum as well as the triglyceride and cholesterol in liver, and increased the HDL-cholesterol/total-cholesterol ratio in serum.
|
|
KEYWORD
|
|
Cheonggukjang, cholesterol, triglyceride, atherogenic index ratios, female rat
|
|
FullTexts / Linksout information
|
|
|
|
Listed journal information
|
|
|
|